Buy RH-34 Cas 1028307-48-3

Buy RH-34 Cas 1028307-48-3

RH-34 is a compound which acts as a potent and selective partial agonist for the 5-HT_2A serotonin receptor subtype. It was derived by structural modification of the selective 5-HT_2A antagonist ketanserin, with the 4-(p-fluorobenzoyl)piperidine moiety replaced by the N-(2-methoxybenzyl) pharmacophore found in such potent 5-HT_2A agonists as NBOMe-2C-B and NBOMe-2C-I. This alteration was found to retain 5-HT_2A affinity and selectivity, but reversed activity from an antagonist to a moderate efficacy partial agonist.^[2][3][4]

RH-34 is a controlled substance in Hungary^[5] and Brazil.^[6] It is not a controlled substance in Canada as of 2025.^[7] It is also not an explicitly controlled substance in the United States.^[8]

• List of miscellaneous 5-HT2A receptor agonists
• EZS-8
• 5-MeO-NBpBrT
• IHCH-7113
• Ketanserin
• Efavirenz

1. RH-34 (CAS 1028307-48-3) is a white, crystalline research chemical with the molecular formula C₁₈H₁₉N₃O₃ and a base molecular weight of 325 g mol⁻¹. Originally derived from the 5-HT₂A antagonist ketanserin, it behaves as a potent and selective partial agonist at the 5-HT₂A serotonin receptor rather than at cannabinoid sites, making it valuable for neuropharmacological studies. Prepared and analytically characterized as its hydrochloride salt (mp 166 °C; MW 361 g mol⁻¹) by the DEA Special Testing and Research Laboratory, RH-34 shows characteristic UV maxima at 226, 279 and 312 nm and distinctive GC-MS, ¹H-NMR and FT-IR signatures. Despite its scientific utility, the compound has no approved medical use, is illegal for human consumption, and is classified as a dangerous substance because its high receptor potency can precipitate unpredictable and severe toxic effects, posing a significant Buy RH-34 Cas 1028307-48-3 public-health risk. Buy RH-34 Cas 1028307-48-3, Buy RH-34 Cas 1028307-48-3, Buy RH-34 Cas 1028307-48-3, Buy RH-34 Cas 1028307-48-3, Buy RH-34 Cas 1028307-48-3, Buy RH-34 Cas 1028307-48-3, Buy RH-34 Cas 1028307-48-3, Buy RH-34 Cas 1028307-48-3, Buy RH-34 Cas 1028307-48-3, Buy RH-34 Cas 1028307-48-3, Buy RH-34 Cas 1028307-48-3, Buy RH-34 Cas 1028307-48-3

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   RH-34 (CAS 1028307-48-3) is a white, crystalline research chemical with the molecular formula C₁₈H₁₉N₃O₃ and a base molecular weight of 325 g mol⁻¹.

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