Buy Ketazocine (ketocyclazocine) Cas 36292-69-0

Buy Ketazocine (ketocyclazocine) Cas 36292-69-0

Ketazocine (INN), also known as ketocyclazocine, is a benzomorphan derivative used in opioid receptor research. Ketazocine, for which the receptor is named, is an exogenous opioid that binds to the κ opioid receptor.^[1]

Activation of this receptor is known to cause sleepiness, a decrease in pain sensation and (potentially) dysphoria, paranoia, and hallucinations. It also causes an increase in urine production because it inhibits the release of vasopressin.

Unlike other opioids, substances that only bind to the κ receptor theoretically do not depress the respiratory system.

The crystal structure of ketazocine was determined in 1983. Buy Ketazocine (ketocyclazocine) Cas 36292-69-0

CAS 36292-69-0

:

Ketocyclazocine

Description:

Ketocyclazocine is a synthetic opioid analgesic that belongs to the class of compounds known as cyclazocines. It is characterized by its complex chemical structure, which includes a ketone functional group and a bicyclic system. Ketocyclazocine exhibits both agonistic and antagonistic properties at opioid receptors, particularly the mu and kappa receptors, which contributes to its analgesic effects. Its pharmacological profile suggests potential applications in pain management, although it may also carry risks of dependence and side effects typical of opioid medications. The substance is typically administered in a controlled setting due to its potency and the potential for abuse. Additionally, Ketocyclazocine has been studied for its effects on the central nervous system, influencing pain perception and mood. As with many opioids, careful consideration of dosage and monitoring for adverse effects are essential in its use. Overall, Ketocyclazocine represents a significant compound in the field of medicinal chemistry, particularly in the development of analgesics. Buy Ketazocine (ketocyclazocine) Cas 36292-69-0

Formula:C₁₈H₂₃NO₂

InChI:InChI=1S/C18H23NO2/c1-11-16-17(21)14-6-5-13(20)9-15(14)18(11,2)7-8-19(16)10-12-3-4-12/h5-6,9,11-12,16,20H,3-4,7-8,10H2,1-2H3/t11-,16-,18+/m0/s1

InChI key:InChIKey=HQBZLVPZOGIAIQ-SDDDUWNISA-N

SMILES:C[C@]12C=3C(C(=O)[C@]([C@@H]1C)(N(CC4CC4)CC2)[H])=CC=C(O)C3

Synonyms: Buy Ketazocine (ketocyclazocine) Cas 36292-69-0, Buy Ketazocine (ketocyclazocine) Cas 36292-69-0, Buy Ketazocine (ketocyclazocine) Cas 36292-69-0, Buy Ketazocine (ketocyclazocine) Cas 36292-69-0, Buy Ketazocine (ketocyclazocine) Cas 36292-69-0, Buy Ketazocine (ketocyclazocine) Cas 36292-69-0, Buy Ketazocine (ketocyclazocine) Cas 36292-69-0, Buy Ketazocine (ketocyclazocine) Cas 36292-69-0, Buy Ketazocine (ketocyclazocine) Cas 36292-69-0, Buy Ketazocine (ketocyclazocine) Cas 36292-69-0

• (-)-Ketocyclazocine
• (2R*,6S*,11S*)-3-(Cyclopropylmethyl)-3,4,5,6-tetrahydro-8-hydroxy-6,11-dimethyl-2,6-methano-3-benzazocin-1(2H)-one
• (2S,6R)-3-(cyclopropylmethyl)-8-hydroxy-6,11-dimethyl-3,4,5,6-tetrahydro-2,6-methano-3-benzazocin-1(2H)-one
• (2S,6R,11R)-3-(Cyclopropylmethyl)-3,4,5,6-tetrahydro-8-hydroxy-6,11-dimethyl-2,6-methano-3-benzazocin-1(2H)-one
• (2S,6R,11R)-3-(cyclopropylmethyl)-8-hydroxy-6,11-dimethyl-3,4,5,6-tetrahydro-2,6-methano-3-benzazocin-1(2H)-one
• 2,6-Methano-3-benzazocin-1(2H)-one, 3-(cyclopropylmethyl)-3,4,5,6-tetrahydro-8-hydroxy-6,11-dimethyl-, (2S,6R,11R)-
• 2,6-Methano-3-benzazocin-1(2H)-one, 3-(cyclopropylmethyl)-3,4,5,6-tetrahydro-8-hydroxy-6,11-dimethyl-, (2alpha,6alpha,11S*)-
• 2,6-Methano-3-benzazocin-1(2H)-one, 3-(cyclopropylmethyl)-3,4,5,6-tetrahydro-8-hydroxy-6,11-dimethyl-, [2S-(2α,6α,11S*)]-
• 3-(Cyclopropylmethyl)-3,4,5,6-tetrahydro-8-hydroxy-6,11-dimethyl-2,6-methano-3-benzazocin-1(2H)-one
• Ketazocina
• See more synonyms

IUPAC Name	(1R,9S,13R)-10-(cyclopropylmethyl)-4-hydroxy-1,13-dimethyl-10-azatricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-8-one	Source
InChI	InChI=1S/C18H23NO2/c1-11-16-17(21)14-6-5-13(20)9-15(14)18(11,2)7-8-19(16)10-12-3-4-12/h5-6,9,11-12,16,20H,3-4,7-8,10H2,1-2H3/t11-,16-,18+/m0/s1	Source
InChI Key	HQBZLVPZOGIAIQ-SDDDUWNISA-N	Source
Canonical SMILES	CC1C2C(=O)C3=C(C1(CCN2CC4CC4)C)C=C(C=C3)O	Source
Isomeric SMILES	C[C@H]1[C@H]2C(=O)C3=C([C@@]1(CCN2CC4CC4)C)C=C(C=C3)O	Source
Molecular Formula	C18H23NO2	Source
Molecular Weight	285.4 g/mol	Source
CAS No.	36292-69-0	Source

Foundational & Exploratory

Ketazocine’s Mechanism of Action at the Kappa Opioid Receptor: A Technical Guide

 

 

The Pharmacological Profile of Ketazocine: A Technical Guide for Benzomorphan Derivatives

 

 

The Discovery and Enduring Legacy of Ketazocine in Opioid Research: A Technical Guide

 

 

An In-Depth Technical Guide to the Chemical Structure and Function of Ketazocine

 

 

The Role of Ketazocine in Understanding Nociception: A Technical Guide

 

 

The Neuropharmacological Profile of Ketazocine: A Technical Guide for Researchers

 

 

An In-Depth Technical Guide to the Interaction of Ketazocine with Endogenous Opioid Systems

 

 

Navigating the Preclinical Landscape of Ketazocine: A Technical Guide to its Pharmacokinetics and Metabolism

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• Benzomorphan
• Ethylketazocine