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1-Boc-4-AP (tert-butyl 4-(phenylamino)piperidine-1-carboxylate) is a compound used as an intermediate in the manufacture of fentanyl, as well as various related derivatives such as butyrylfentanyl, furanylfentanyl, benzylfentanyl and homofentanyl, among others. It is an N-protected derivative of 4-anilinopiperidine which can be readily converted to fentanyl or related analogues in several straightforward synthetic steps. It was classified as a DEA List 1 Chemical in 2022, and is also controlled in various other jurisdictions. Its possession, sale and importation are consequently heavily regulated throughout much of the world.[1] 1-Boc-4-AP has also been identified as an impurity in other designer drug products, though it is unclear if it has any pharmacological activity in its own right. Buy 4-ANBocP N-Boc-4-AP Cas 125541-22-2
Cas 125541-22-2
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Buy 1-Boc-4-AP Cas 125541-22-2. 1-Boc-4-AP (tert-butyl 4-(phenylamino)piperidine-1-carboxylate) is a compound used as an intermediate in the manufacture of fentanyl, as well as various related derivatives such as butyrylfentanyl, furanylfentanyl, benzylfentanyl and homofentanyl, among others. It is an N-protected derivative of 4-anilinopiperidine which can be readily converted to fentanyl or related analogues in several straightforward synthetic steps. It was classified as a DEA List 1 Chemical in 2022, and is also controlled in various other jurisdictions. Its possession, sale and importation are consequently heavily regulated throughout much of the world. 1-Boc-4-AP has also been identified as an impurity in other designer drug products, though it is unclear if it has any pharmacological activity in its own right. Buy 1-Boc-4-AP Cas 125541-22-2
1-N-Boc-4-(Phenylamino)piperidine
- CAS No.
- 125541-22-2
- Chemical Name: Buy 4-ANBocP N-Boc-4-AP Cas 125541-22-2
- 1-N-Boc-4-(Phenylamino)piperidine
- Synonyms
- tert-butyl 4-anilinopiperidine-1-carboxylate;1-Boc-4-(phenylaMino)piperidine;tert-butyl 4-(phenylaMino)piperidine-1-carboxylate;1-N-Boc-4-(Phenylamino);Aniline piperidine;(Phenylamino)piperidine;4-(Phenylamino)piperidine, N1-BOC protected;2-Methyl-2-propanyl 4-anilino-1-piperidinecarboxylate;4-(phenylamino)-;1-N-Boc-4-(Phenylami
- CBNumber:
- CB2262675
- Molecular Formula:
- C16H24N2O2
- Molecular Weight:
- 276.37
- MDL Number:
- MFCD02102489
- MOL File:
- 125541-22-2.mol
| Melting point | 136-137 |
|---|---|
| Boiling point | 400.6±38.0 °C(Predicted) |
| Density | 1.107±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | DMF: 15mg/mL; DMSO: 25mg/mL; Ethanol: 25mg/mL; Ethanol:PBS (pH 7.2) (1:1): 0.5mg/mL |
| form | A crystalline solid |
| pka | 5.00±0.20(Predicted) |
| InChI | InChI=1S/C16H24N2O2/c1-16(2,3)20-15(19)18-11-9-14(10-12-18)17-13-7-5-4-6-8-13/h4-8,14,17H,9-12H2,1-3H3 |
| InChIKey | HTIWISWAPVQGMI-UHFFFAOYSA-N |
| SMILES | N1(C(OC(C)(C)C)=O)CCC(NC2=CC=CC=C2)CC1 |
| FDA UNII | 5PB6P54SRS |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 22 | |||||||||
| Hazard Note | Harmful/Irritant | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 2933399990 | |||||||||
| NFPA 704 |
|
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1-N-Boc-4-(Phenylamino) piperidine Basic info
Product name:1-N-Boc-4-(Phenylamino) piperidine
Alias:tert-Butyl 4-anilinopiperidine-1-carboxylate;4-Anilino-1-Boc-piperidine
CAS:125541-22-2
MF:C16H24N2O2
MW:276.37
Assay:99%min
Appearance:white powder
Packing:25KG/ cardboard drum or upon customers’ request.
1-N-Boc-4-(Phenylamino) piperidine uses:Pharmaceutical Intermediates
1-N-Boc-4-(Phenylamino) piperidine description:
1-N-Boc-4-(Phenylamino) piperidine function:
1-N-Boc-4-(Phenylamino) piperidine application:
used as a pharmaceutical intermediates.Intermediate in the preparation of Fentanyl derivatives.
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1-N-Boc-4-(Phenylamino)piperidine Chemical Properties,Uses,Production
Description
4-Anilino-1-Boc-piperidine is an analytical reference standard that is structurally similar to known opioids. 4-Anilino-1-Boc-piperidine is a precursor in the synthesis of 4-anilinopiperidine . This product is intended for research and forensic applications.
Chemical Properties
Pale Brown Solid
Uses
Intermediate in the preparation of Fentanyl derivatives.
Application
1-N-Boc-4-(Phenylamino)piperidine is an amino acid derivative widely employed as a reagent in organic synthesis. This compound exhibits remarkable versatility, finding applications in various fields such as peptide and protein synthesis, organic synthesis, and drug development. It possesses strong basic properties, allowing for diverse reactions with acids that lead to the formation of a wide array of products. The extensive use of this compound in organic synthesis is well-documented, particularly in the synthesis of peptides and proteins. By facilitating the coupling of amino acids, it enables the creation of peptides that can be utilized in diverse applications, including the development of pharmaceutical drugs.
1-N-Boc-4-(Phenylamino)piperidine Preparation Products And Raw materials
Raw materials
Preparation Products
125541-22-2(1-N-Boc-4-(Phenylamino)piperidine)Related Search:
Cas 125541-22-2
4-Anilino-1-Boc-piperidine is an analytical reference standard that is structurally similar to known opioids. It is a precursor in the synthesis of 4-anilinopiperidine . This product is intended for research and forensic applications.
| Cas No. | 125541-22-2 | SDF | |
| Synonyms | 4-ANBocP, N-Boc-4-AP, 1-Boc-4-(Phenylamino)piperidine, tert-Butyl 4-(phenylamino)piperidine-1-carboxylate | ||
| Canonical SMILES | O=C(OC(C)(C)C)N(CC1)CCC1NC2=CC=CC=C2 | ||
| Formula | C16H24N2O2 | M.Wt | 276.4 |
| Solubility | DMF: 15mg/mL,DMSO: 25mg/mL,Ethanol: 25mg/mL,Ethanol:PBS (pH 7.2) (1:1): 0.5mg/mL | Storage | Store at -20°C |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
||
| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
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1-N-Boc-4-(Phenylamino) piperidine Basic info
Product name:1-N-Boc-4-(Phenylamino) piperidine
Alias:tert-Butyl 4-anilinopiperidine-1-carboxylate;4-Anilino-1-Boc-piperidine
CAS:125541-22-2
MF:C16H24N2O2
MW:276.37
Assay:99%min
Appearance:white powder
Packing:25KG/ cardboard drum or upon customers’ request.
1-N-Boc-4-(Phenylamino) piperidine uses:Pharmaceutical Intermediates
1-N-Boc-4-(Phenylamino) piperidine description:
1-N-Boc-4-(Phenylamino) piperidine function:
1-N-Boc-4-(Phenylamino) piperidine application:
used as a pharmaceutical intermediates.Intermediate in the preparation of Fentanyl derivatives.
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- CAS No.：125541-22-2
| 1-N-Boc-4-(Phenylamino)piperidine Basic information |
| Product Name: | 1-N-Boc-4-(Phenylamino)piperidine |
| Synonyms: | TERT-BUTYL 4-ANILINOTETRAHYDRO-1(2H)-PYRIDINECARBOXYLATE;4-(Phenylamino)piperidine, N1-BOC protected;1-N-BOC-4-(PHENYLAMINO)PIPERIDINE;tert-butyl 4-anilinotetrahydro-1(2H)-pyridinecarboxylate (en);N-tert-Butoxycarbonyl-4-anilinopiperidine; 1-N-Boc-4-(Pheny 1-N-Boc-4-(Phenylamino)piperidinelamino)piperidine;1-N-Boc-4-(Phenylamino)piperidine Supplier;1-N-Boc-4-(Phenylamino) |
| CAS: | 125541-22-2 |
| MF: | C16H24N2O2 |
| MW: | 276.37 |
| EINECS: | 203-105-0 |
| Product Categories: | Intermediates;inter;Aromatics;Heterocycles;pharmaceutical;Intermediate;125541-22-2;Pharm |
| Mol File: | 125541-22-2.mol |
| 1-N-Boc-4-(Phenylamino)piperidine Chemical Properties |
| Melting point | 136-137 |
| Boiling point | 400.6±38.0 °C(Predicted) |
| density | 1.107±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| pka | 5.00±0.20(Predicted) |
| Safety Information |
| Hazard Codes | Xi,Xn |
| Risk Statements | 22 |
| Hazard Note | Harmful/Irritant |
| HazardClass | IRRITANT |
| HS Code | 2933399990 |
| 1-N-Boc-4-(Phenylamino)piperidine Usage And Synthesis |
| Description | 4-Anilino-1-Boc-piperidine (Item No. 29119) is an analytical reference standard that is structurally similar to known opioids. 4-Anilino-1-Boc-piperidine is a precursor in the synthesis of 4-anilinopiperidine . This product is intended for research and forensic applications. |
| Chemical Properties | Pale Brown Solid |
| Uses | Intermediate in the preparation of Fentanyl derivatives. |
| 1-N-Boc-4-(Phenylamino)piperidine Preparation Products And Raw materials |
| Preparation Products | N-phenylpiperidin-4-amine–>N-PHENYLPIPERIDIN-4-AMINE DIHYDROCHLORIDE |
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Basic information.
| CBNumber: | CB3280285 |
| Chemical Name: | 1-BOC-4-(4-FLUORO-PHENYLAMINO)-PIPERIDINE |
| Molecular Formula: | C16H23FN2O2 |
| Formula Weight: | 294.36 |
| CAS No.: | 288573-56-8 |
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N-Phenethyl-4-piperidinone – Wikipedia
What is NPP in Chemistry?
An Efficient, Optimized Synthesis of Fentanyl and Related
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