Buy N-Phenethyl-4-piperidinone (NPP) Cas 39742-60-4
Buy N-Phenethyl-4-piperidinone (NPP) Cas 39742-60-4
N-Phenethyl-4-piperidinone (NPP) is a derivative of 4-piperidinone with the molecular formula C13H17NO. It is used as an intermediate in the manufacture of chemicals and pharmaceutical drugs such as fentanyl.
Because of its possible use in the illicit manufacture of fentanyl, the United States Drug Enforcement Administration (DEA) placed NPP under control as a List 1 Chemical in 2007. Both domestic sales and domestic importations are thus subject to DEA reporting requirements.[3]
Preparation
[edit]
N-Phenethyl-4-piperidinone can be prepared from 4-piperidinone and phenethyl bromide in biphasic conditions with a variety of phase transfer catalysts.[citation needed] Buy N-Phenethyl-4-piperidinone (NPP) Cas 39742-60-4
Uses
[edit]
N-Phenethyl-4-piperidinone is useful in the synthesis of addictive drugs, primarily fentanyl and its analogs. Paul Janssen (founder of Janssen Pharmaceutica) first synthesized fentanyl in 1960 from Benzylfentanyl.[4] The Siegfried method (shown below and published on The Hive) involves reacting N-phenethyl-4-piperidinone with aniline, and then reducing the imine product with sodium borohydride to 4-anilino-N-phenethylpiperidine (ANPP). This product is reacted with propionyl chloride to form fentanyl.
Buy N-Phenethyl-4-piperidinone (NPP) Cas 39742-60-4
Buy N-Phenethyl-4-piperidinone (NPP) Cas 39742-60-4. N-Phenethyl-4-piperidinone (NPP) is a derivative of 4-piperidinone with the molecular formula C13H17NO. It is used as an intermediate in the manufacture of chemicals and pharmaceutical drugs such as fentanyl.
Because of its possible use in the illicit manufacture of fentanyl, the United States Drug Enforcement Administration (DEA) placed NPP under control as a List 1 Chemical in 2007. Both domestic sales and domestic importations are thus subject to DEA reporting requirements. Buy N-Phenethyl-4-piperidinone (NPP) Cas 39742-60-4
| N-Phenethyl-4-piperidinone | |
|---|---|
| IUPAC name | 1-(2-Phenylethyl)piperidin-4-one |
| Other names | N-Phenethyl-4-piperidinone |
| Abbreviations | NPP |
| Identifiers | |
| CAS number | |
| SMILES | C1CN(CCC1=O)CCC2=CC=CC=C2 |
| Properties | |
| Molecular formula | C13H17NO |
| Molar mass | 203.28 g mol-1 |
| Hazards | |
| EU classification | Flammable (F) Harmful (Xn) Dangerous for the environment (N) |
| NFPA 704 |
3
1
0
|
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references Buy SSD Solution Online |
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Preparation
[edit]
N-Phenethyl-4-piperidinone can be prepared from 4-piperidinone and phenethyl bromide in biphasic conditions with a variety of phase transfer catalysts.[citation needed]
Uses
[edit]
N-Phenethyl-4-piperidinone is useful in the synthesis of addictive drugs, primarily fentanyl and its analogs. Paul Janssen (founder of Janssen Pharmaceutica) first synthesized fentanyl in 1960 from Benzylfentanyl.[4] The Siegfried method (shown below and published on The Hive) involves reacting N-phenethyl-4-piperidinone with aniline, and then reducing the imine product with sodium borohydride to 4-anilino-N-phenethylpiperidine (ANPP). This product is reacted with propionyl chloride to form fentanyl.
Buy N-Phenethyl-4-piperidinone (NPP) Cas 39742-60-4
Buy N-Phenethyl-4-piperidinone (NPP) Cas 39742-60-4
Buy N-Phenethyl-4-piperidinone (NPP) Cas 39742-60-4
Buy N-Phenethyl-4-piperidinone (NPP) Cas 39742-60-4
Buy N-Phenethyl-4-piperidinone (NPP) Cas 39742-60-4
Buy N-Phenethyl-4-piperidinone (NPP) Cas 39742-60-4
Buy N-Phenethyl-4-piperidinone (NPP) Cas 39742-60-4
Buy N-Phenethyl-4-piperidinone (NPP) Cas 39742-60-4
Buy N-Phenethyl-4-piperidinone (NPP) Cas 39742-60-4
Buy N-Phenethyl-4-piperidinone (NPP) Cas 39742-60-4
Buy N-Phenethyl-4-piperidinone (NPP) Cas 39742-60-4
1-Phenethylpiperidin-4-one ,
N-Phenylethyl-4-piperidinone,
N-Phenethyl-4-piperidone,
References
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NPP (CAS 39742-60-4) – Cayman Chem
NPP: An Analytical Reference Standard. CAS Number: 39742-60-4. Synonyms: NSC 74494, N-Phenethyl-4-piperidone, 1-Phenethyl-4-piperidone. Purity: ≥98%.
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N-Phenethyl-4-piperidinone (NPP) – CAS 39742-60-4
N-Phenethyl-4-piperidinone is used as an intermediate in the manufacture of chemicals and pharmaceutical drugs such as fentanyl. It is a derivative of 4-piperidinone with the molecular …
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Buy 1-Phenethyl-4-piperidone | 39742-60-4 | BenchChem
With the quality product at a COMPETITIVE price, you can focus more on your research. 1-Phenethyl-4-piperidone (CAS: 39742-60-4; molecular formula: C₁₃H₁₇NO) is a piperidine …
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N-Phenethyl-4-piperidone (NPP) solution – MilliporeSigma
N-Phenethyl-4-piperidone (NPP) solution 1 mg/mL in acetonitrile, certified reference material, ampule of 1 mL, Cerilliant®; CAS Number: 39742-60-4 at Sigma-Aldrich
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Purchase N Phenethylpiperidinone | Sarchem Labs
Jun 25, 2021 · Looking for N Phenethylpiperidinone from the best chemical supplier in USA. Our chemicals are available from quotation & order to efficient global delivery.
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CAS ID: 39742-60-4
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Molecular Formula: C13H17NO
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IUPAC Name: 1- (2-phenylethyl)piperidin-4-one
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Molecular Weight: 203.285
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N-phenethyl-4-piperidone (Cas 39742-60-4) – Parchem
Parchem supplies N-phenethyl-4-piperidone and a range of specialty chemicals worldwide
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1-Phenethyl-4-piperidone | 39742-60-4 – ChemicalBook
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CAS No : 39742-60-4 | Product Name : 1-Phenethyl-4 …
Buy highly pure 1-Phenethyl-4-piperidone, CAS No : 39742-60-4, Mol.Formula : C13H17NO, Mol.Weight : 203.29, from Pharmaffiliates. Login as registered …
Buy N-Phenethyl-4-piperidinone (NPP) Cas 39742-60-4
Buy N-Phenethyl-4-piperidinone (NPP) Cas 39742-60-4. N-Phenethyl-4-piperidinone (NPP) is a derivative of 4-piperidinone with the molecular formula C 13 H 17 NO. It is used as an …
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