Buy Metenolone acetate (Primobolan) Cas 434-05-9
Buy Metenolone acetate (Primobolan) Cas 434-05-9
Metenolone acetate, or methenolone acetate, sold under the brand names Primobolan and Nibal, is an androgen and anabolic steroid (AAS) medication which is used mainly in the treatment of anemia due to bone marrow failure.[1][2][3][4][5][6] It is taken by mouth.[5] Although it was widely used in the past, the drug has mostly been discontinued and hence is now mostly no longer available.[4][5][2] A related drug, metenolone enanthate, is given by injection into muscle.[5]
Side effects of metenolone acetate include symptoms of masculinization like acne, increased hair growth, voice changes, and increased sexual desire.[5] The drug is a synthetic androgen and anabolic steroid and hence is an agonist of the androgen receptor (AR), the biological target of androgens like testosterone and dihydrotestosterone (DHT).[5][7] It has moderate anabolic effects and weak androgenic effects, as well as no estrogenic effects or risk of liver damage.[5][7] Metenolone enanthate is a metenolone ester and a prodrug of metenolone in the body.[5]
Metenolone acetate was introduced for medical use in 1961.[8][5] In addition to its medical use, metenolone acetate is used to improve physique and performance.[5] The drug is a controlled substance in many countries and so non-medical use is generally illicit.[5] It remains marketed for medical use only in a few countries, such as Japan and Moldova. Buy Metenolone acetate (Primobolan) Cas 434-05-9, Buy Metenolone acetate (Primobolan) Cas 434-05-9, Buy Metenolone acetate (Primobolan) Cas 434-05-9, Buy Metenolone acetate (Primobolan) Cas 434-05-9, Buy Metenolone acetate (Primobolan) Cas 434-05-9, Buy Metenolone acetate (Primobolan) Cas 434-05-9, Buy Metenolone acetate (Primobolan) Cas 434-05-9, Buy Metenolone acetate (Primobolan) Cas 434-05-9, Buy Metenolone acetate (Primobolan) Cas 434-05-9, Buy Metenolone acetate (Primobolan) Cas 434-05-9, Buy Metenolone acetate (Primobolan) Cas 434-05-9, Buy Metenolone acetate (Primobolan) Cas 434-05-9, Buy Metenolone acetate (Primobolan) Cas 434-05-9, Buy Metenolone acetate (Primobolan) Cas 434-05-9, Buy Metenolone acetate (Primobolan) Cas 434-05-9
CAS 434-05-9 Methenolone Acetate
Product Name:Methenolone Acetate
Alias:Primobolan Acetate
CAS Registry Number:434-05-9
EINECS: 207-097-0
Molecular Formula: C22H32O3
Molecular Weight: 344.4877
Assay: 99% min.
Grade : Pharmaceutical Grade
Appearance: White crystalline powder.
Primobolan Benefits
Primobolan is considered a fairly weak steroid. Its anabolic/androgenic ratings are low and it’s one of the weakest steroids on paper; though, it is stronger than masteron. Since masteron is always related to cutting cycles, on paper primo should gain credibility as a cutting steroid.
Primo has a huge advantage over most steroids, as it’s stronger than testosterone at binding to the androgen receptor. As with most dihydrotestosterone (DHT) related AAS, it’s a good aid for fat loss. In addition, primo doesn’t aromatize, so you won’t need an aromatase inhibitor (AI) or SERM with it. Interesting fact, primobolan was tested by old-school bodybuilders as gynecomastia (gyno) treatment back in the 70s and 80s. As strange as it sounds, it has been medically proven to reduce breast tumors in women (which are mainly estrogen related).
Since primobolan increases nitrogen retention, it’s been touted as anti-catabolic, and somewhat anabolic (which can be disputed). In simple terms, it helps you keep your muscle mass while you’re dieting. That’s one of the biggest reasons it’s used on cutting cycles. Anecdotally, evidence shows that by using primobolan during low-calorie diets (even 20-30% below your BMR), you can keep your current lean muscle while gaining new muscle tissue. While this seems to be against basic understanding of nutrition, we’ll chuck this one to the magic of steroids.
Primobolan Side Effects
As Primobolan does not aromatize many of the common anabolic steroid associated side-effects are non-existent. Side-effects such as water retention and bloat are very rare and Gynecomastia is of little concern. Further, as the oral version is not a 17-aa steroid liver damage largely goes out the window. Without question this is one of the safest steroids on the market but make no mistake, possible side-effects do exist. Like all DHT based steroids Primobolan can cause hair-loss. There is something you need to understand about hair-loss, steroids that promote this do not make you go bald, you were going to go bald anyway but if you are predisposed to this condition DHT steroids like Primobolan will simply speed it up. Beyond hair-loss and virilization in women who abuse the steroid there is little concern when this steroid is used; however, testosterone suppression must be mentioned and discussed as there is a prevailing myth in this regard.
Methenolone Acetate Dosage
Methenolone Acetate is the injectable version of the steroid methenolone powders.The effective dose of Primobolan (Methenolone Acetate) in the type of injection is 200-300 mg weekly. In case you want to take this drug by mouth, 50-150 mg in a day is the directed measure. For men, 50-100 mgs /day is the accurate as well actual measure by mouth, while for women, 10-25 mgs /day is the finest quantity. If you have to administrate them as injections, the top dose for Primobolan (Methenolone Acetate) injection is 350-600 mg/week for men. Women have to use 100 mg weekly of this medication. Primobolan (Methenolone Acetate) injectable active life is near ten-fortheen days, while the dynamic life of this medicine in the form of pills is approximate 4-6 hours. The time of its finding is four-five weeks
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- Research Chemicals: Available in small quantities for laboratory use via Biosynth.
- Analytical Standards: Traceable API standards and certified reference materials can be requested via LGC Standards.
Methenolone acetate | 434-05-9 | FM177344
Researchers conducting chronic oral AAS studies in rodent models often face confounding hepatotoxicity from 17α-alkylated steroids. Methenolone acetate (CAS 434-05-9) addresses this with its C1-methylated structure, which significantly reduces hepatic stress while preserving a myotrophic-to-androgenic index of 7-enabling cleaner dissection of anabolic vs. androgenic pathways. • C1-Methylation avoids 17α-alkylation hepatotoxicity; validated by lower liver enzyme elevation in long-term animal studies. • Myotrophic/androgenic ratio of 7 vs. nandrolone decanoate (10.6-12.1) facilitates targeted mechanistic research. • RP-HPLC validated method available for purity verification; extensive metabolite profile (12+ metabolites) documented for forensic and analytical applications.
Technical Parameters
Basic Identity
| Product Name | Methenolone acetate |
|---|---|
| CAS | 434-05-9 |
| Synonyms | metenolone acetate methenolone acetate methenolone acetate, (17beta)-isomer Primobolan Primobolan S |
| Molecular Formula | C22H32O3 |
| Molecular Weight | 344.5 g/mol |
Structural Identifiers
| SMILES | CC1=CC(=O)CC2C1(C3CCC4(C(C3CC2)CCC4OC(=O)C)C)C |
|---|---|
| InChI | InChI=1S/C22H32O3/c1-13-11-16(24)12-15-5-6-17-18-7-8-20(25-14(2)23)21(18,3)10-9-19(17)22(13,15)4/h11,15,17-20H,5-10,12H2,1-4H3/t15-,17-,18-,19-,20-,21-,22-/m0/s1 |
| InChIKey | PGAUJQOPTMSERF-QWQRBHLCSA-N |
Commercial & Availability
| Standard Pack Sizes | 5 mg / 20 mg / 100 mg / 1 g / Bulk Custom |
|---|---|
| Availability | In Stock |
| Custom Synthesis | Available on request |
Handling Information
| Appearance | Solid powder |
|---|---|
| Solubility | Soluble in DMSO |
| Storage | Dry, dark and at 0 – 4 C for short term (days to weeks) or -20 C for long term (months to years). |
Structure & Identifiers
Methenolone Acetate (CAS 434-05-9) Procurement Guide: Key Characteristics and Research Utility
Methenolone acetate (CAS 434-05-9) is a synthetic, orally active anabolic-androgenic steroid (AAS) and a 1-methylated derivative of dihydrotestosterone (DHT) . It is the C17β acetate ester prodrug of the active compound methenolone [1]. Primarily employed in research settings, it is recognized for its moderate anabolic effects and relatively low androgenic activity .
Methenolone Acetate (CAS 434-05-9) vs. Generic AAS: Why Structural and Metabolic Differences Preclude Simple Substitution
Methenolone acetate’s structural modification, a C1-methyl group instead of the common C17α-alkylation found in other oral AAS, fundamentally alters its metabolism and safety profile . This unique feature significantly reduces hepatic stress compared to 17α-alkylated analogues like oxandrolone or stanozolol [1]. Therefore, assuming functional equivalence with other orally active AAS can lead to inaccurate conclusions regarding in vivo pharmacokinetics and hepatotoxicity in research models .
Quantitative Differentiation Guide for Methenolone Acetate (CAS 434-05-9)
Differentiation by Anabolic-to-Androgenic (A/A) Ratio: Methenolone Acetate vs. Nandrolone Decanoate
Methenolone acetate demonstrates a more favorable myotrophic-to-androgenic index compared to nandrolone decanoate in preclinical models. This difference is critical for studies aiming to maximize anabolic tissue effects while minimizing androgenic stimulation [1].
Structural Rationale for Reduced Hepatic Toxicity: Methenolone Acetate vs. 17α-Alkylated Oral Steroids
Unlike most orally active AAS, methenolone acetate achieves oral bioavailability via C1-methylation rather than C17α-alkylation . This structural difference is directly linked to a lower hepatic toxicity profile compared to its 17α-alkylated analogues [1].
Analytical Verification: Validated RP-HPLC Method for Methenolone Acetate in Complex Matrices
A validated, selective, and accurate RP-HPLC method has been developed for the analytical characterization of methenolone acetate, specifically for its identification in complex matrices like nutritional supplements [1]. This method provides a reliable, quantitative tool for quality assurance and research purposes.
In Vivo Metabolism: Urinary Excretion Profile of Methenolone Acetate in Humans
Following a single 50 mg oral dose, cumulative urinary excretion of the parent compound, methenolone, accounted for only 1.63% of the ingested dose over 90 hours [1]. This indicates extensive biotransformation, yielding at least twelve distinct metabolites [1].
Anabolic Steroids Primobolan-depot Methenolone Acetate for Muscle Growth CAS 434-05-9
Product name Methenolone Acetate
Alias primobolone;Primobolan-depot
CAS Number 434-05-9
EINECS 207-097-0
MF C22H32O3
MW 344.4877
Appearance White crystalline powder.
Assay 99% min.
Melting Point 144°C~136 °C
Loss on drying ≤0.5
Specific rotation °+59~°+50
Residue on ignition: ≤0.1
Standard: Enterprise standard
What is the half-life of Primobolan acetate?
While it is stronger with a 10.5-day half-life, this form is no longer synthesized and outmoded nowadays. Methenolone Acetate: It is the oral/pill form that binds to the small acetate ester and has a 4-6 hour active life.
What is the lifespan of Primobolan?
As an oral tablet it is known as methenolone acetate. Active life: oral methenolone (4-6 hours); liquid (injectable) methenolone (10-14 days).
What is the best way to cycle Primobolan?
Best Primobolan Cycle
If you’re using the oral form of Primobolan, most experts recommend a dose of 50-100 mg per day. If you’re using the injectable form, a dose of 200-400mg per week is typically sufficient. When it comes to deciding how long to cycle Primobolan, there is no hard and fast rule
Is methenolone an anabolic steroid?
Metenolone, or methenolone, is an androgen and anabolic steroid (AAS) which is used in the form of esters such as metenolone acetate (brand name Primobolan, Nibal) and metenolone enanthate (brand name Primobolan Depot, Nibal Injection).
Is methenolone enanthate Primobolan or Primo?
Metenolone enanthate (methenolone enanthate) is an ester derivative of methenolone sold commonly under the brand names Primobolan (tablet form) orPrimobolan Depot (injectable). When it interacts with the aromatase enzyme it does not form any estrogens
How long should you cycle Primobolan?
A standard duration for continuing the Primobolan doses is 8-12 weeks. During this time, one can build tolerance and reap optimum effects without facing the full-blown complications of the steroid. Once you complete your cycle, do not kick-start another for at least an 8-week period.
What is the best way to cycle Primobolan?
Best Primobolan Cycle
If you’re using the oral form of Primobolan, most experts recommend a dose of 50-100 mg per day. If you’re using the injectable form, a dose of 200-400mg per week is typically sufficient. When it comes to deciding how long to cycle Primobolan, there is no hard and fast rule
What is the use of methenolone acetate in bodybuilding?
Metenolone enanthate, or methenolone enanthate, sold under the brand names Primobolan Depot and Nibal Injection, is an androgen and anabolic steroid (AAS) medication which is used mainly in the treatment of anemia due to bone marrow failure. It is given by injection into muscle.
COA
| Test | Standard | Results |
| Description | White Or Almost White Crystalline Powder | White Crystalline Powder |
| Melting Point | 139℃~ 145℃ | 139.5℃~ 142.5℃ |
| Loss On Drying | ≤0.50% | 0.34% |
| Specific Rotation | +55°~ +58° | +57.4° |
| Assay | 97~102% | 98.66% |
| Conclusion | The specification conform with Enterprise Standard. | |
| HOT Product | CAS |
| Testosterone enanthate | 315-37-7 |
| Testosterone cypionate | 58-20-8 |
| Testosterone propionate | 57-85-2 |
| Testosterone decanoate | 5721-91-5 |
| Testosterone undecanoate | 5949-44-0 |
| Testosterone Isocaproate | 15262-86-9 |
| Testosteron base | 58-22-0 |
| Testosterone acetate | 1045-69-8 |
| Methyl testosterone | 58-18-4 |
| Testosterone phenylpropionate | 1255-49-8 |
| Sustanon 250 / Testosterone Blend | / |
| Methyltrienolone | 965-93-5 |
| Proviron / Mesterolone | 1424-00-6 |
| Fluoxymesterone / Halotestin / Halo | 76-43-7 |
| Dianabol / Methandrostenolone | 72-63-9 |
| Anavar/ Oxandrolone | 53-39-4 |
| Oxymetholone /Anadrol | 434-07-1 |
| Tamoxifen Citrate/ nolvadex | 10540-29-1 |
| Drostanolone enanthate / Masteron enanthate | 13425-31-5 |
| Drostanolone propionate / Masteron propionate | 521-12-0 |
| Trenbolone Acetate | 10161-34-9 |
| Trenbolone enanthate | 1629618-98-9 |
| Trenbolone Hexahydrobenzyl Carbonate / Parabolan | 23454-33-3 |
| equipoise / Boldenoe undecylenate | 13103-34-9 |
| Boldenone cypionate | 106505-90-2 |
| Boldenone acetate | 2363-59-9 |
| Methenolone Acetate / Primobolan | 434-05-9 |
| Methenolone Enanthate / primobolin | 303-42-4 |
| Nandrolone | 434-22-0 |
| Nandrolone decanoate | 360-70-3 |
| Nandrolone phenylpropionate | 62-90-8 |
| turinabol / 4-Chlorodehydromethyltestosterone | 855-19-6 |
| Clomiphene Citrate / Clomid | 50-41-9 |
| Exemestane / Aromasin | 107868-30-4 |
| Letrozole / Femara | 112809-51-5 |
| Anastrozole | 120511-73-1 |
| Estriol | 50-27-1 |
| Estradiol | 50-28-2 |
| Stanozolol / Winstrol powder injectable | 10418-03-8 |
| Stanozolol / Winstrol powder oral | 10418-03-8 |
| Sildenafil / Viagra | 139755-83-2 |
| Tadalafil / Cialis | 171596-29-5 |
| Superdrol / Methasterone | 3381-88-2 |
| Progesterone | 57-83-0 |
| Clenbuterol | 37148-27-9 |
| BCAA | / |
| DHT/Dihydrotestosterone | 521-18-6 |
| 2, 4Dinitrophenol/DNP | 51-28-5 |
| Progesterone | 57-83-0 |
| Estradiol | 50-28-2 |
Validated Application Scenarios for Methenolone Acetate (CAS 434-05-9) in Research and Quality Control
Investigations of Selective Anabolic Signaling and Structure-Activity Relationships (SAR)
Based on its myotrophic-to-androgenic index ratio of 7, which is distinctly lower than that of nandrolone decanoate (10.6-12.1) [1], methenolone acetate is an ideal tool for studies aimed at dissecting anabolic versus androgenic signaling pathways. Its specific A/A ratio allows researchers to probe receptor-mediated effects with a comparatively reduced androgenic component in rodent models.
Long-Term In Vivo Studies Requiring Minimized Hepatic Confounders
For chronic administration studies in animals, the C1-methylated structure of methenolone acetate provides a crucial advantage. Its reported lower hepatic toxicity compared to the class of 17α-alkylated oral AAS [2] makes it a more suitable candidate for long-duration experiments where minimizing liver damage is critical for data integrity and animal welfare.
Quality Control and Adulterant Detection in Dietary Supplements
The validated RP-HPLC method developed by Peikova et al. [3] provides a robust, specific, and accurate protocol for the identification and quantification of methenolone acetate in complex matrices like nutritional supplements. This method is directly applicable for analytical chemistry, forensic toxicology, and regulatory compliance laboratories tasked with monitoring the presence of this substance in commercial products.
Forensic Toxicology and Anti-Doping Metabolite Analysis
Research requiring the detection of methenolone acetate use must account for its extensive metabolism. Human data shows that only 1.63% of an oral dose is excreted as the parent compound, while at least twelve metabolites are formed [4]. This established metabolic profile is essential for developing and validating analytical methods (e.g., GC-MS, LC-MS/MS) for detecting its use in forensic or anti-doping contexts.
Technical Documentation Hub
Structured technical reading across foundational, methodological, troubleshooting, and validation/comparative pathways. Use the hub when you need more detail before procurement.
The Pharmacological Profile of Methenolone Acetate: A Technical Guide
Methenolone Acetate and its Interaction with the Androgen Receptor: A Technical Guide
In-Vitro Anabolic Effects of Methenolone Acetate: A Technical Guide
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